

ISMP Medication Safety Alert!® Acute Care Newsletter - 2025 Single Issues
The ISMP Medication Safety Alert!® Acute Care is a digital newsletter for hospital healthcare professionals, including Directors of Pharmacy, Pharmacists, Nurses, Physicians, Medication and Patient Safety Officers, Risk Managers, or anyone concerned with medication safety.
Volume 30, Issue 1
In this issue:
- MERP Annual Review Exposes How Manufacturer Labeling/Quality Issues Impact Medication Safety
- Entire insulin infusion administered at fluid rate
- Topical agent packaged similarly to an injectable vial
- Budesonide prescribed instead of bumetanide results in readmission
- Vaccine registry not checked before administration
Volume 30, Issue 2
In this issue:
- Do Not Cut Scopolamine or CloNIDine Patches to Deliver Partial Medication Doses
- Provide order clarity when medications are to be given in divided doses
- Do not use unapproved EPINEPHrine nasal solutions
- Incorrect concentration of dextrose infusions prepared during shortage
- Acute Care Action Agenda (October – December 2024)
Volume 30, Issue 3
In this issue:
- Another Case of Nursing Criminalization – Long-Term Care (LTC) Must Improve Systems, Not Blame Nurses – Part I
- Medication syringes may be mistaken for sodium chloride flush
- Lack of electronic health record (EHR) integration between health systems leads to incomplete medication lists
- Epoprostenol reconstituted incorrectly
Volume 30, Issue 4
In this issue:
- A Deeper Dive into Active Failures and Accountability Using Just Culture Principles – Part II
- Danziten and Tasigna are NOT interchangeable nilotinib formulations
- Magnesium almost administered instead of heparin
- Remembering James Reason
- Worth repeating… Patient developed methemoglobinemia after administration of Hurricaine spray
Volume 30, Issue 5
In this issue:
- Survey Exposes Risks with Custom and Multi-Chamber Parenteral Nutrition – Part I
- Infusion errors can still occur with interoperability
- Esmolol labeled as “DOUBLE STRENGTH” may lead to confusion
Volume 30, Issue 6
In this issue:
- Action Needed to Address Risk with Custom and Multi-Chamber Bag Parenteral Nutrition – Part II
- Syringe design hinders emergency medication delivery
- Manufacturer’s levETIRAcetam 1,000 mg/100 mL premixed IV bags mislabeled as 500 mg/100 mL
- Prevent intravenous lipid bag mix-up with ViperSlide
- PCC – Prothrombin complex concentrate or protein C concentrate?
Volume 30, Issue 7
In this issue:
- Implement Strategies to Prevent Persistent Medication Errors and Hazards: 2025
- Medication vial coring and fragmentation risks
- Your Reports at Work: Label changes help differentiate Amneal infusion bags
- Survey on Implementation of Targeted Best Practices
Volume 30, Issue 8
In this issue:
- Food-Drug Allergies – Inactive Ingredients Taking Active Roles
- Cyanokit – action needed!
- Alpha-gal syndrome – evaluate inactive ingredients
- Acute Care Action Agenda (January – March 2025)
Volume 30, Issue 9
In this issue:
- Respiratory Therapists Play a Critical Role in Medication Safety
- Never dilute medication in a syringe labeled as a saline flush
- More mix-ups with rifamycin antibiotics
- Changes to Hikma’s vancomycin reconstitution instructions
Volume 30, Issue 10
In this issue:
- Call to Action: Practitioners Need to Warn Patients About Purchasing Counterfeit Drugs Online
- DiazePAM 10 mg/2 mL prefilled syringe label design may result in incorrect dose
- Pink vial caps lead to close call with high-alert medications
Volume 30, Issue 11
In this issue:
- Do You Know What Is Going on in Your OR? The Anesthesiology Residents’ Perspective
- Formalin almost administered instead of sterile water
- Caution: Drug names that end with the letter “l”
- Close call with 0.9% and 3% sodium chloride bags
- EPINEPHrine auto-injector without retractable needle
Volume 30, Issue 12
In this issue:
- Prevent Potentially Catastrophic Drug Overdoses by Properly Configuring Various Technologies
- Multiple Barcode and Dates on Oxytocin Bags
- Hazard! Broselow Rainbow Tape contains incorrect information
- Paralytic agent mistaken for insulin
- Do not use non-sterile ultrasound gel for percutaneous procedures
Volume 30, Issue 13
In this issue:
- Lost in Transition: Evaluate and Mitigate Risks During Interfacility Transfers
- Is it ceFAZolin or penicillin G potassium?
- Abrysvo diluent syringe design hinders vaccine reconstitution
Volume 30, Issue 14
In this issue:
- Why Scan “Harmless” Saline Infusions and Flush Syringes? It Might Not be What You Think!
- Remembering Dr. Lucian Leape
- Topical medication in luer syringe was injected
- Hiberix diluent syringe administered as vaccine
Volume 30, Issue 15
In this issue:
- Time-Saving Bias – Time to Rethink the Need for Speed
- Your Reports at Work: Sandoz ceFAZolin recall
- Review and update parenteral nutrition order forms and order sets
- Updated guidelines for electronic communication
- Acute Care Action Agenda (April – June 2025)
Volume 30, Issue 16
In this issue:
- Enhance Interoperability Workflow and End User Alerts to Ensure Meaningful Action
- Contaminated WG Critical Care calcium gluconate 2,000 m g/100 mL bag
- Irrigation solution infused intravenously
Volume 30, Issue 17
In this issue:
- Take Action on the Top Five Themes Identified During ISMP Consultations
- Worth repeating…Patient given oral cromolyn via nebulizer – again!
- Warning! Overwrap labeled potassium chloride 10 mEq/100 mL may contain potassium chloride 20 mEq/50 mL premixed IV bag
- IV push propofol almost administered via amnioinfusion line
Volume 30, Issue 18
In this issue:
- Safeguard Pediatric Patients – Act Upon the 2025 KIDs List
- Another Potentially Contaminated Calcium Gluconate Bag – Now by Amneal
- Barcode Scanning Is Crucial to Prevent Mix-Ups with Similar-Looking Heparin Bags
- Norepinephrine Mistaken for Similar-Looking Vials of Multivitamin Injection
Volume 30, Issue 19
In this issue:
- Support Practitioners Through Second Victim Programs
- Priorix Packaging – Possibility of Diluent Being Given Without the Vaccine
- Methohexital Syringes Mistaken for Similar-Looking Ketamine
Volume 30, Issue 20
In this issue:
- Raising the Bar – Zoning in on Barcode Medication Administration Practices
- Titratable Infusions Call for an Interdisciplinary Approach
- Include Implantable Medication Pumps in Patients’ Medication Histories
Volume 30, Issue 21
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Volume 30, Issue 22
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Volume 30, Issue 23
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Volume 30, Issue 24
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Volume 30, Issue 25
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