Guidelines for Sterile Compounding and the Safe Use of Sterile Compounding Technology

Identify best practices to support safe use of technology and automation in sterile compounding.

Criminalization of Human Error and a Guilty Verdict: A Travesty of Justice that Threatens Patient Safety

On March 25, 2022, most of the healthcare community were shocked and dismayed after learning that RaDonda Vaught had been convicted of criminally negligent homicide and gross neglect of an impaired...

Addressing Disrespectful Behaviors and Creating a Respectful, Healthy Workplace–Part II

In late 2021, ISMP conducted a survey on disrespectful behaviors in healthcare. Any behavior that discourages the willingness of staff or patients to speak up or interact with an individual because...

Survey Suggests Disrespectful Behaviors Persist in Healthcare: Practitioners Speak Up (Yet Again) – Part I

In our September 9, 2021 newsletter, we discussed the topic of disrespectful behaviors, which have persisted in healthcare for years. Unfortunately, too many remain silent or make excuses in an att...

Medication Safety Issues with Newly Authorized PAXLOVID

On December 22, 2021, the US Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for PAXLOVID, consisting of oral tablets of nirmatrelvir that are co-packaged with oral t...

NAN Alert! Age-Related COVID-19 Vaccine Mix-Ups

Ever since the US Food and Drug Administration (FDA) authorized the emergency use of a specific formulation (10 mcg/0.2 mL) of the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine for ch...

High-Alert Medications in Community/Ambulatory Care Settings

Medications requiring special safeguards to reduce the risk of errors and minimize harm.

High-Alert Medications in Long-Term Care (LTC) Settings

Medications requiring special safeguards to reduce the risk of errors and minimize harm.

Medication Safety Self Assessment® for Perioperative Settings

Designed to heighten awareness of safe practices in Perioperative Settings.

Just Culture, Medication Error Prevention, and Second Victim Support: A Better Prescription for Preparing Nursing Students for Practice

A white paper that serves as a call to action to nursing programs to change the way they are preparing students.

Additional Strategies to Improve Complete Delivery of Small-Volume Intermittent Infusions

In the December 3, 2020 newsletter, ISMP published an article to remind practitioners that up to half of the medication in a 50 mL small-volume intermittent infusion (medication diluted in a small ...

A Recurring Call to Action: Every Healthcare Organization Needs a Medication Safety Officer!

Medication safety is a serious responsibility that is vital to the sustainability of healthcare organizations.1 On average, hospitalized patients experience one medication error each day,2,3 and pr...

Hidden Medication Loss When Using a Primary Administration Set for Small-Volume Intermittent Infusions

While covering for a colleague during patient rounds in an adult medical unit, a pharmacist noticed two empty 50 mL minibags of ZOSYN (piperacillin and tazobactam) hanging on a patient’s intravenou...

NAN Alert! Dangerous Wrong-Route Errors with Tranexamic Acid

We recently learned about three cases of accidental spinal injection of tranexamic acid instead of a local anesthetic intended for regional (spinal) anesthesia. Container mix-ups were involved in e...

The Differences Between Human Error, At-Risk Behavior, and Reckless Behavior Are Key to a Just Culture

Do you believe your organization operates within a Just Culture? We have asked this question many times while working collaboratively with healthcare organizations and professionals. It is not an e...

Guidelines for Optimizing Safe Implementation and Use of Smart Infusion Pumps

Developed in 2020 to help healthcare facilities standardize smart infusion pump technology.

Four Ways to Say No to Adverse Drug Reactions

The seeds of an adverse drug interaction can be planted at any point in the care process, by any of the individuals involved. For instance, take a look at these common scenarios: A clinician, over...

Speaking Up About Patient Safety Requires an Observant Questioner and a High Index of Suspicion

Healthcare practitioners are expected to speak up about patient safety concerns to help intercept errors and avoid adverse patient outcomes. By ‘speaking up,’ we mean raising concerns for the benef...

Independent Double Checks: Worth the Effort if Used Judiciously and Properly

Manual independent double checks of certain high-alert medications have been widely promoted in healthcare to help detect potentially harmful errors before they reach patients.1,2 Many practitioner...

Dangerous Wrong-Route Errors with Tranexamic Acid—A Major Cause for Concern

Problem: Earlier this month, we were notified about two cases of accidental intraspinal injection of tranexamic acid, occurring in two different states. Unfortunately, the report was sent anonymous...

Guidelines for the Safe Use of Automated Dispensing Cabinets

Standard best practices and processes directly associated with ADC design and functionality.